SODIUM DEPLETION AND RENAL CONSERVATION OF WATER*

Sodium depletion and renal conservation of water.

Chloride depletion and hypochloraemia as a cause of renal sodium and water loss in the rat.

1. To study the effects of chloride depletion, without sodium depletion or change in plasma tonicity, on renal excretion of sodium and water, a single exchange peritoneal dialysis was performed in rats against a solution of glucose (15 g/1) containing either NaCl (150 mmol/l, control) or NaHCO3 (150 mmol/l, experimental); KHCO3 (4mmol/l)was added to both solutions. All rats were prepared before...

Breviscapine prevents downregulation of renal water and sodium transport proteins in response to unilateral ureteral obstruction

Objective(s):Our recent report indicates that breviscapine play a protective role of the kidney by down-regulating transforming growth factor-β1(TGF-β1), α-smooth muscle actin (α-SMA) and alleviating interstitial fibrosis following unilateral ureteral obstruction (UUO). In this study, we investigate the effect of breviscapine on changes of renal water and sodium transport proteins in response t...

Opioid Control of Renal Excretion of Water and Sodium

27 * Department of Pharmacology, School of Pharmacy, Marmara University, T›bbiye Cad. No: 49 Haydarpafla, 81010 Istanbul, Turkey ° Corresponding author Opioid Control of Renal Excretion of Water and Sodium Summary : The kidneys act to regulate total body water and sodium via numerous neural and humoral mechanisms, including pathways that involve the renal sympathetic nerves, antidiuretic hormon...

Hormonal regulation of renal sodium and water excretion during normotensive sodium loading in conscious dogs.

Saline was infused intravenously for 90 min to normal, sodium-replete conscious dogs at three different rates (6, 20, and 30 micromol x kg(-1) x min(-1)) as hypertonic solutions (HyperLoad-6, HyperLoad-20, and HyperLoad-30, respectively) or as isotonic solutions (IsoLoad-6, IsoLoad-20, and IsoLoad-30, respectively). Mean arterial blood pressure did not change with any infusion of 6 or 20 microm...